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Prioritize LDL-C to help reduce ASCVD risk for your patients.2,4
National Health and Nutritional Examination Survey (NHANES) Coronary Heart Disease (CHD) data show that from 2017 to 20205b:
~9.3 million American adults had a myocardial infarction5
~9.4 million American adults had a stroke, 87% of which were ischemic5
bIn March 2020, the COVID-19 pandemic halted NHANES field operations. Because data collected in the partial 2019 to 2020 cycle are not nationally representative, they were combined with previously released 2017 to 2018 data to produce nationally representative estimates. CHD includes people who responded “yes” to at least 1 of the questions in “Has a doctor or other health professional ever told you that you had CHD, angina or AP, heart attack, or MI?”5
Elevated LDL-C is a major causal risk factor for ASCVD5
Do you know how many patients with ASCVD are not achieving their LDL-C goal?
AP=angina pectoris; ASCVD=atherosclerotic cardiovascular disease; CHD=coronary heart disease; CVD=cardiovascular disease; LDL-C=low density lipoprotein cholesterol; MI=myocardial infarction; NHANES=National Health and Nutritional Examination Survey.
References: 1. Writing Committee; Lloyd-Jones DM, Morris PB, et al. 2022 ACC Expert Consensus Decision Pathway on the Role of Nonstatin Therapies for LDL-Cholesterol Lowering in the Management of Atherosclerotic Cardiovascular Disease Risk: A Report of the American College of Cardiology Solution Set Oversight Committee. J Am Coll Cardiol. 2022;80(14):1366-1418. doi:10.1016/j.jacc.2022.07.006 2. Domanski MJ, Tian X, Wu CO, et al. Time Course of LDL Cholesterol Exposure and Cardiovascular Disease Event Risk. J Am Coll Cardiol. 2020;76(13):1507-1516. doi:10.1016/j.jacc.2020.07.059 3. Ference BA, Braunwald E, Catapano AL. The LDL Cumulative Exposure Hypothesis: Evidence and Practical Applications. Nat Rev Cardiol. 2024;21(10):701-716. doi:10.1038/s41569-024-01039-5 4. Ference BA, Graham I, Tokgozoglu L, et al. Impact of Lipids on Cardiovascular Health: JACC Health Promotion Series. J Am Coll Cardiol. 2018;72(10):1141-1156. doi:10.1016/j.jacc.2018.06.046 5. Martin SS, Aday AW, Allen NB, et al; American Heart Association Council on Epidemiology and Prevention Statistics Committee and Stroke Statistics Committee. 2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association. Circulation. 2025;151(8):e41-e660. doi:10.1161/CIR.0000000000001303